Upcoming Events:

Dark Genome Symposium

Nov 20-21, 2024, NYU Langone, New York

Co-hosted by ROME Therapeutics, Enara Bio, Nucleome Therapeutics, and NYU Langone


SyRGe Publications:

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Systems genomics in age-related macular degeneration.

den Hollander et al. Experimental Eye Research. 2022.


Two differentially stable rDNA loci coexist on the same chromosome and form a single nucleolus.

Lazar-Stefanita et al. Proceedings of the National Academy of Sciences. 2023.




Immune and Genome Engineering as the Future of Transplantable Tissue.

Elisseeff et al. The New England Journal of Medicine. 2021.


A versatile platform for locus-scale genome rewriting and verification.

Brosh, Laurent et al. Proceedings of the National Academy of Sciences. 2021.






Synthetic Genomes

Zhang et al. Annual Review of Biochemistry. 2020.





Additional Publications:

Genomic context sensitivity of insulator function.

André M. Ribeiro-dos-Santos et al. Genome Research. 2022.




Check out also:


Synthetic Yeast 2.0

Learn about our ongoing project to synthesize a designer eukaryotic genome.


The Yeast Art Project

The goal of the Yeast Art Project is to connect individuals to the process of scientific exploration.

The project gives us the opportunity to visualize many of the essential processes in basic biology research. 



The Boeke Lab at NYU Langone Health


The Maurano Lab at NYU Langone Health